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Ranking Enzyme Structures in the PDB by Bound Ligand Similarity to Biological Substrates

There are numerous applications that use the structures of protein-ligand complexes from the PDB, such as 3D pharmacophore identification, virtual screening, and fragment-based drug design. The structures underlying these applications are potentially much more informative if they contain biologicall...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Tyzack, Jonathan D., Fernando, Laurent, Ribeiro, Antonio J.M., Borkakoti, Neera, Thornton, Janet M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890617/
https://ncbi.nlm.nih.gov/pubmed/29551288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.02.009
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