Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

One approach to identifying cancer-specific vulnerabilities and therapeutic targets is to profile genetic dependencies in cancer cell lines. Here, we describe data from a series of siRNA screens that identify the kinase genetic dependencies in 117 cancer cell lines from ten cancer types. By integrat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Campbell, James, Ryan, Colm J., Brough, Rachel, Bajrami, Ilirjana, Pemberton, Helen N., Chong, Irene Y., Costa-Cabral, Sara, Frankum, Jessica, Gulati, Aditi, Holme, Harriet, Miller, Rowan, Postel-Vinay, Sophie, Rafiq, Rumana, Wei, Wenbin, Williamson, Chris T., Quigley, David A., Tym, Joe, Al-Lazikani, Bissan, Fenton, Timothy, Natrajan, Rachael, Strauss, Sandra J., Ashworth, Alan, Lord, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802229/
https://ncbi.nlm.nih.gov/pubmed/26947069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.023
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados