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Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells

PARP inhibitors have been proposed as a potential targeted therapy for patients with triple-negative (ER-, PR-, HER2-negative) breast cancers. However, it is as yet unclear as to whether single agent or combination therapy using PARP inhibitors would be most beneficial. To better understand the mech...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bajrami, Ilirjana, Kigozi, Asha, Van Weverwijk, Antoinette, Brough, Rachel, Frankum, Jessica, Lord, Christopher J, Ashworth, Alan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: WILEY-VCH Verlag 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491838/
https://ncbi.nlm.nih.gov/pubmed/22933245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201250
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