Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells

PARP inhibitors have been proposed as a potential targeted therapy for patients with triple-negative (ER-, PR-, HER2-negative) breast cancers. However, it is as yet unclear as to whether single agent or combination therapy using PARP inhibitors would be most beneficial. To better understand the mech...

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Главные авторы: Bajrami, Ilirjana, Kigozi, Asha, Van Weverwijk, Antoinette, Brough, Rachel, Frankum, Jessica, Lord, Christopher J, Ashworth, Alan
Формат: Artigo
Язык:Inglês
Опубликовано: WILEY-VCH Verlag 2012
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491838/
https://ncbi.nlm.nih.gov/pubmed/22933245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201250
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