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A Chemogenomic Analysis of Ionization Constants - Implications for Drug Discovery
Chemogenomics methods seek to characterize the interaction between drugs and biological systems and are an important guide for the selection of screening compounds. The acid/base character of drugs has a profound influence on their affinity for the receptor, on their absorption, distribution, metabo...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777741/ https://ncbi.nlm.nih.gov/pubmed/23303535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201200507 |
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