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The Significance of Acid/Base Properties in Drug Discovery
While drug discovery scientists take heed of various guidelines concerning drug-like character, the influence of acid/base properties often remains under-scrutinised. Ionisation constants (pK(a) values) are fundamental to the variability of the biopharmaceutical characteristics of drugs and to under...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641858/ https://ncbi.nlm.nih.gov/pubmed/23099561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cs35348b |
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