Lataa...
The human endogenous metabolome as a pharmacology baseline for drug discovery
We have limited understanding of the variation in in vitro affinities of drugs for their targets. An analysis of a highly curated set of 442 interactions between 293 drugs and 79 primary targets reveals that 67% of drug–target affinities have values above that of the corresponding endogenous ligand,...
Tallennettuna:
| Julkaisussa: | Drug Discov Today |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2019
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7748399/ https://ncbi.nlm.nih.gov/pubmed/31226432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2019.06.007 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|