Cranberry Product Decreases Fat Accumulation in Caenorhabditis elegans

Por Sun, Quancai, Yue, Yiren, Shen, Peiyi, Yang, Jeremy J., Park, Yeonhwa
Publicado no J Med Food (2016)

Badapple: promiscuity patterns from noisy evidence

Por Yang, Jeremy J., Ursu, Oleg, Lipinski, Christopher A., Sklar, Larry A., Oprea, Tudor I., Bologa, Cristian G.
Publicado no J Cheminform (2016)

REDIAL-2020: A suite of machine learning models to estimate Anti-SARS-CoV-2 activities

Por Govinda, KC, Bocci, Giovanni, Verma, Srijan, Hassan, Mahmudulla, Holmes, Jayme, Yang, Jeremy J., Sirimulla, Suman, Oprea, Tudor I.
Publicado no ChemRxiv (2020)

The CARLSBAD Database: A Confederated Database of Chemical Bioactivities

Por Mathias, Stephen L., Hines-Kay, Jarrett, Yang, Jeremy J., Zahoransky-Kohalmi, Gergely, Bologa, Cristian G., Ursu, Oleg, Oprea, Tudor I.
Publicado em 2013

DrugCentral: online drug compendium

Por Ursu, Oleg, Holmes, Jayme, Knockel, Jeffrey, Bologa, Cristian G., Yang, Jeremy J., Mathias, Stephen L., Nelson, Stuart J., Oprea, Tudor I.
Publicado no Nucleic Acids Res (2017)

DrugCentral 2018: an update

Por Ursu, Oleg, Holmes, Jayme, Bologa, Cristian G, Yang, Jeremy J, Mathias, Stephen L, Stathias, Vasileios, Nguyen, Dac-Trung, Schürer, Stephan, Oprea, Tudor
Publicado no Nucleic Acids Res (2019)

Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing

Por Oprea, Tudor I., Nielsen, Sonny Kim, Ursu, Oleg, Yang, Jeremy J., Taboureau, Olivier, Mathias, Stephen L., Kouskoumvekaki, lrene, Sklar, Larry A., Bologa, Cristian G.
Publicado em 2011

How to Illuminate the Druggable Genome using Pharos

Por Sheils, Timothy, Mathias, Stephen L., Siramshetty, Vishal B., Bocci, Giovanni, Bologa, Cristian G., Yang, Jeremy J., Waller, Anna, Southall, Noel, Nguyen, Dac-Trung, Oprea, Tudor I.
Publicado no Curr Protoc Bioinformatics (2020)

Formalizing drug indications on the road to therapeutic intent

Por Nelson, Stuart J, Oprea, Tudor I, Ursu, Oleg, Bologa, Cristian G, Zaveri, Amrapali, Holmes, Jayme, Yang, Jeremy J, Mathias, Stephen L, Mani, Subramani, Tuttle, Mark S, Dumontier, Michel
Publicado no J Am Med Inform Assoc (2017)

TIN-X: target importance and novelty explorer

Por Cannon, Daniel C, Yang, Jeremy J, Mathias, Stephen L, Ursu, Oleg, Mani, Subramani, Waller, Anna, Schürer, Stephan C, Jensen, Lars Juhl, Sklar, Larry A, Bologa, Cristian G, Oprea, Tudor I
Publicado no Bioinformatics (2017)

DrugCentral 2021 supports drug discovery and repositioning

Por Avram, Sorin, Bologa, Cristian G, Holmes, Jayme, Bocci, Giovanni, Wilson, Thomas B, Nguyen, Dac-Trung, Curpan, Ramona, Halip, Liliana, Bora, Alina, Yang, Jeremy J, Knockel, Jeffrey, Sirimulla, Suman, Ursu, Oleg, Oprea, Tudor I
Publicado no Nucleic Acids Res (2020)

Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 3. Fused Uracil-Containing Heterocycles as Novel Topoisomerase-Targeting Agents

Por Evdokimov, Nikolai M., Van slambrouck, Severine, Heffeter, Petra, Tu, Lee, Le Calvé, Benjamin, Lamoral-Theys, Delphine, Hooten, Carla J., Uglinskii, Pavel Y., Rogelj, Snezna, Kiss, Robert, Steelant, Wim F.A., Berger, Walter, Yang, Jeremy J., Bologa, Cristian G., Kornienko, Alexander, Magedov, Igor V.
Publicado em 2011

TCRD and Pharos 2021: mining the human proteome for disease biology

Por Sheils, Timothy K, Mathias, Stephen L, Kelleher, Keith J, Siramshetty, Vishal B, Nguyen, Dac-Trung, Bologa, Cristian G, Jensen, Lars Juhl, Vidović, Dušica, Koleti, Amar, Schürer, Stephan C, Waller, Anna, Yang, Jeremy J, Holmes, Jayme, Bocci, Giovanni, Southall, Noel, Dharkar, Poorva, Mathé, Ewy, Simeonov, Anton, Oprea, Tudor I
Publicado no Nucleic Acids Res (2020)

Drug target ontology to classify and integrate drug discovery data

Por Lin, Yu, Mehta, Saurabh, Küçük-McGinty, Hande, Turner, John Paul, Vidovic, Dusica, Forlin, Michele, Koleti, Amar, Nguyen, Dac-Trung, Jensen, Lars Juhl, Guha, Rajarshi, Mathias, Stephen L., Ursu, Oleg, Stathias, Vasileios, Duan, Jianbin, Nabizadeh, Nooshin, Chung, Caty, Mader, Christopher, Visser, Ubbo, Yang, Jeremy J., Bologa, Cristian G., Oprea, Tudor I., Schürer, Stephan C.
Publicado no J Biomed Semantics (2017)

Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays

Por Lee, Jonathan A., Shinn, Paul, Jaken, Susan, Oliver, Sarah, Willard, Francis S., Heidler, Steven, Peery, Robert B., Oler, Jennifer, Chu, Shaoyou, Southall, Noel, Dexheimer, Thomas S., Smallwood, Jeffrey, Huang, Ruili, Guha, Rajarshi, Jadhav, Ajit, Cox, Karen, Austin, Christopher P., Simeonov, Anton, Sittampalam, G. Sitta, Husain, Saba, Franklin, Natalie, Wild, David J., Yang, Jeremy J., Sutherland, Jeffrey J., Thomas, Craig J.
Publicado no PLoS One (2015)

Unexplored therapeutic opportunities in the human genome

Por Oprea, Tudor I., Bologa, Cristian G., Brunak, Søren, Campbell, Allen, Gan, Gregory N., Gaulton, Anna, Gomez, Shawn M., Guha, Rajarshi, Hersey, Anne, Holmes, Jayme, Jadhav, Ajit, Jensen, Lars Juhl, Johnson, Gary L., Karlson, Anneli, Leach, Andrew R., Ma’ayan, Avi, Malovannaya, Anna, Mani, Subramani, Mathias, Stephen L., McManus, Michael T., Meehan, Terrence F., von Mering, Christian, Muthas, Daniel, Nguyen, Dac-Trung, Overington, John P., Papadatos, George, Qin, Jun, Reich, Christian, Roth, Bryan L., Schürer, Stephan C., Simeonov, Anton, Sklar, Larry A., Southall, Noel, Tomita, Susumu, Tudose, Ilinca, Ursu, Oleg, Vidovic, Dušica, Waller, Anna, Westergaard, David, Yang, Jeremy J., Zahoránszky-Köhalmi, Gergely
Publicado no Nat Rev Drug Discov (2018)