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Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing

Finding new uses for old drugs is a strategy embraced by the pharmaceutical industry, with increasing participation from the academic sector. Drug repurposing efforts focus on identifying novel modes of action, but not in a systematic manner. With intensive data mining and curation, we aim to apply...

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Autori principali: Oprea, Tudor I., Nielsen, Sonny Kim, Ursu, Oleg, Yang, Jeremy J., Taboureau, Olivier, Mathias, Stephen L., Kouskoumvekaki, lrene, Sklar, Larry A., Bologa, Cristian G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266123/
https://ncbi.nlm.nih.gov/pubmed/22287994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.201100023
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