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A high throughput flow cytometric assay platform targeting transporter inhibition
This review highlights the concepts, recent applications and limitations of High Throughput Screening (HTS) flow cytometry-based efflux inhibitory assays. This platform has been employed in mammalian and yeast efflux systems leading to the identification of small molecules with transporter inhibitor...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101541/ https://ncbi.nlm.nih.gov/pubmed/25027381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2014.03.010 |
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