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A novel flow-cytometric assay to identify inhibitors of RBPJ-DNA interactions
Notch signaling is often involved in cancer cell initiation and proliferation. Aberrant Notch activation underlies more than 50% of T-cell Acute Lymphoblastic Leukemia (T-ALL); accordingly, chemicals disrupting Notch signaling are of potential to treat Notch-dependent cancer. Here, we developed a fl...
Enregistré dans:
| Publié dans: | SLAS Discov |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442708/ https://ncbi.nlm.nih.gov/pubmed/32567455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555220932552 |
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