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A high throughput flow cytometric assay platform targeting transporter inhibition

This review highlights the concepts, recent applications and limitations of High Throughput Screening (HTS) flow cytometry-based efflux inhibitory assays. This platform has been employed in mammalian and yeast efflux systems leading to the identification of small molecules with transporter inhibitor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tegos, George P., Evangelisti, Annette M., Strouse, J. Jacob, Ursu, Oleg, Bologa, Cristian G., Sklar, Larry A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101541/
https://ncbi.nlm.nih.gov/pubmed/25027381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2014.03.010
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