Capter 11 Filtering in Drug Discovery

Por Lipinski, Christopher A.
Publicado no Annu Rep Comput Chem (2005)

The Pyk2 FERM domain: a Novel Therapeutic Target

Por Lipinski, Christopher A., Loftus, Joseph C.
Publicado em 2010

The rule of five should not impede anti-parasitic drug development

Por McKerrow, James H., Lipinski, Christopher A.
Publicado no Int J Parasitol Drugs Drug Resist (2017)

Computational Prediction and Validation of an Expert's Evaluation of Chemical Probes

Por Litterman, Nadia K., Lipinski, Christopher A., Bunin, Barry A., Ekins, Sean
Publicado no J Chem Inf Model (2014)

Structural Conservation in Band 4.1, Ezrin, Radixin, Moesin (FERM) Domains as a Guide To Identify Inhibitors of the Proline-Rich Tyrosine Kinase 2

Por Meurice, Nathalie, Wang, Lei, Lipinski, Christopher A., Yang, Zhongbo, Hulme, Christopher, Loftus, Joseph C.
Publicado em 2010

Flashback phenomenon and residual neurological deficits after the use of “bath salt” 3, 4- methylenedioxypyrovalerone

Por Mangold, Aaron R., Bravo, Thomas P, Traub, Stephen J., Maher, Steven A., Lipinski, Christopher A.
Publicado em 2014

Parallel Worlds of Public and Commercial Bioactive Chemistry Data: Miniperspective

Por Lipinski, Christopher A., Litterman, Nadia K., Southan, Christopher, Williams, Antony J., Clark, Alex M., Ekins, Sean
Publicado no J Med Chem (2014)

Badapple: promiscuity patterns from noisy evidence

Por Yang, Jeremy J., Ursu, Oleg, Lipinski, Christopher A., Sklar, Larry A., Oprea, Tudor I., Bologa, Cristian G.
Publicado no J Cheminform (2016)

Extended survival of Pyk2 or FAK deficient orthotopic glioma xenografts

Por Lipinski, Christopher A., Tran, Nhan L., Viso, Carole, Kloss, Jean, Yang, Zhongbo, Berens, Michael E., Loftus, Joseph C.
Publicado em 2008

The Pyk2 FERM domain as a target to inhibit glioma migration

Por Loftus, Joseph C., Yang, Zhongbo, Tran, Nhan L., Kloss, Jean, Viso, Carole, Berens, Michael E., Lipinski, Christopher A.
Publicado em 2009

The Tyrosine Kinase Pyk2 Promotes Migration and Invasion of Glioma Cells

Por Lipinski, Christopher A, Tran, Nhan L, Menashi, Emmanuel, Rohl, Carole, Kloss, Jean, Bay, R Curtis, Berens, Michael E, Loftus, Joseph C
Publicado em 2005

Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824

Por Li, Xiaojin, Manjunatha, Ujjini H., Goodwin, Michael B., Knox, John E., Lipinski, Christopher A., Keller, Thomas H., Barry, Clifton E., Dowd, Cynthia S.
Publicado em 2008

Serum Lactate and Mortality in Emergency Department Patients with Cancer

Por Maher, Steven A., Temkit, M’hamed, Buras, Matthew R., McLemore, Ryan Y., Butler, Rebecca K., Chowdhury, Yasmynn, Lipinski, Christopher A., Traub, Stephen J.
Publicado no West J Emerg Med (2018)

A Crowdsourcing Evaluation of the NIH Chemical Probes

Por Oprea, Tudor I., Bologa, Cristian G., Boyer, Scott, Curpan, Ramona F., Glen, Robert C., Hopkins, Andrew L., Lipinski, Christopher A., Marshall, Garland R., Martin, Yvonne C., Ostopovici-Halip, Liliana, Rishton, Gilbert, Ursu, Oleg, Vaz, Roy J., Waller, Chris, Waldmann, Herbert, Sklar, Larry A.
Publicado em 2009