Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824

Lignende værker

• Structure-Activity Relationships of Antitubercular Nitroimidazoles. 3. Exploration of the Linker and Lipophilic Tail of ((S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-(4-trifluoromethoxybenzyl)amine (6-amino PA-824)
  af: Cherian, Joseph, et al.
  Udgivet: (2011)
• Development of (6R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis
  af: Thompson, Andrew M., et al.
  Udgivet: (2018)
• Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis
  af: Manjunatha, Ujjini H., et al.
  Udgivet: (2006)
• Mycobacterium leprae Is Naturally Resistant to PA-824
  af: Manjunatha, Ujjini H., et al.
  Udgivet: (2006)
• The effect of 5-substitution on the electrochemical behavior and antitubercular activity of PA-824
  af: Bollo, Soledad, et al.
  Udgivet: (2010)