The MEP pathway: Promising drug targets in the fight against tuberculosis

nork Wang, Xu, Dowd, Cynthia S.
Argitaratua izan da ACS Infect Dis (2018)

Phosphonate prodrugs: an overview and recent advances

nork Heidel, Kenneth M, Dowd, Cynthia S
Argitaratua izan da Future Med Chem (2019)

Novel route to 5-position vinyl derivatives of thiolactomycin: Olefination vs. deformylation

nork Kim, Pilho, Barry, Clifton E., Dowd*, Cynthia S.
Argitaratua 2006

Vitamin in the Crosshairs: Targeting Pantothenate and Coenzyme A Biosynthesis for New Antituberculosis Agents

nork Butman, Hailey S., Kotzé, Timothy J., Dowd, Cynthia S., Strauss, Erick
Argitaratua izan da Front Cell Infect Microbiol (2020)

SYNTHESIS AND SPECTROSCOPIC DIFFERENTIATION OF 2- AND 4-ALKOXYTHIOTETRONIC ACIDS

nork Shenoy, Gautham, Kim, Pilho, Goodwin, Michael, Nguyen, Quynh-Anh, Barry, Clifton E., Dowd*, Cynthia S.
Argitaratua 2004

Mycobacterium leprae Is Naturally Resistant to PA-824

nork Manjunatha, Ujjini H., Lahiri, Ramanuj, Randhawa, Baljit, Dowd, Cynthia S., Krahenbuhl, James L., Barry, Clifton E.
Argitaratua 2006

9-aminoacridine Inhibition of HIV-1 Tat Dependent Transcription

nork Guendel, Irene, Carpio, Lawrence, Easley, Rebecca, Van Duyne, Rachel, Coley, William, Agbottah, Emmanuel, Dowd, Cynthia, Kashanchi, Fatah, Kehn-Hall, Kylene
Argitaratua 2009

Synthetic Fosmidomycin Analogues with Altered Chelating Moieties Do Not Inhibit 1-Deoxy-d-xylulose 5-phosphate Reductoisomerase or Plasmodium falciparum Growth In Vitro

nork Chofor, René, Risseeuw, Martijn D.P., Pouyez, Jenny, Johny, Chinchu, Wouters, Johan, Dowd, Cynthia S., Couch, Robin D., Van Calenbergh, Serge
Argitaratua izan da Molecules (2014)

Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation

nork Dubrovsky Larisa, Dowd Cynthia S, Klase Zachary, Castro Iris, Zweier Lynnsey, Pedati Caitlin, Kehn-Hall Kylene, Wu Weilin, Bukrinsky Michael, Kashanchi Fatah
Argitaratua 2008-03-01

Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation

nork Wu, Weilin, Kehn-Hall, Kylene, Pedati, Caitlin, Zweier, Lynnsey, Castro, Iris, Klase, Zachary, Dowd, Cynthia S, Dubrovsky, Larisa, Bukrinsky, Michael, Kashanchi, Fatah
Argitaratua 2008

The effect of 5-substitution on the electrochemical behavior and antitubercular activity of PA-824

nork Bollo, Soledad, Núñez-Vergara, Luis J., Kang, Sunhee, Zhang, Liang, Boshoff, Helena I., Barry, Clifton E., Squella, Juan A., Dowd, Cynthia S.
Argitaratua 2010

Antibacterial and Antitubercular Activity of Fosmidomycin, FR900098, and their Lipophilic Analogs

nork Uh, Eugene, Jackson, Emily R., Jose, Géraldine San, Maddox, Marcus, Lee, Robin E., Lee, Richard E., Boshoff, Helena I., Dowd, Cynthia S.
Argitaratua 2011

Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824

nork Li, Xiaojin, Manjunatha, Ujjini H., Goodwin, Michael B., Knox, John E., Lipinski, Christopher A., Keller, Thomas H., Barry, Clifton E., Dowd, Cynthia S.
Argitaratua 2008

Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD(+)) synthetase inhibitors as potential antitubercular agents

nork Wang, Xu, Ahn, Yong-Mo, Lentscher, Adam G., Lister, Julia S., Brothers, Robert C., Kneen, Malea M., Gerratana, Barbara, Boshoff, Helena I., Dowd, Cynthia S.
Argitaratua izan da Bioorg Med Chem Lett (2017)

Structure-activity relationships of antitubercular nitroimidazoles. I. Structural features associated with aerobic and anaerobic activities of 4- and 5-nitroimidazoles

nork Kim, Pilho, Zhang, Liang, Manjunatha, Ujjini H., Singh, Ramandeep, Patel, Sejal, Jiricek, Jan, Keller, Thomas H., Boshoff, Helena I., Barry, Clifton E., Dowd, Cynthia S.
Argitaratua 2009

Lipophilic Prodrugs of FR900098 Are Antimicrobial against Francisella novicida In Vivo and In Vitro and Show GlpT Independent Efficacy

nork McKenney, Elizabeth S., Sargent, Michelle, Khan, Hameed, Uh, Eugene, Jackson, Emily R., Jose, Géraldine San, Couch, Robin D., Dowd, Cynthia S., van Hoek, Monique L.
Argitaratua 2012

Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis

nork Manjunatha, Ujjini H., Boshoff, Helena, Dowd, Cynthia S., Zhang, Liang, Albert, Thomas J., Norton, Jason E., Daniels, Lacy, Dick, Thomas, Pang, Siew Siew, Barry, Clifton E.
Argitaratua 2006

The effect of chain length and unsaturation on Mtb Dxr inhibition and antitubercular killing activity of FR900098 analogs

nork Jackson, Emily R., Jose, Géraldine San, Brothers, Robert C., Edelstein, Emma K., Sheldon, Zachary, Haymond, Amanda, Johny, Chinchu, Boshoff, Helena I., Couch, Robin D., Dowd, Cynthia S.
Argitaratua 2013

Design of Potential Bisubstrate Inhibitors against Mycobacterium tuberculosis (Mtb) 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (Dxr)—Evidence of a Novel Binding Mode

nork San Jose, Géraldine, Jackson, Emily R., Uh, Eugene, Johny, Chinchu, Haymond, Amanda, Lundberg, Lindsay, Pinkham, Chelsea, Kehn-Hall, Kylene, Boshoff, Helena I., Couch, Robin D., Dowd, Cynthia S.
Argitaratua 2013

Kinetic Characterization and Allosteric Inhibition of the Yersinia pestis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (MEP Synthase)

nork Haymond, Amanda, Johny, Chinchu, Dowdy, Tyrone, Schweibenz, Brandon, Villarroel, Karen, Young, Richard, Mantooth, Clark J., Patel, Trishal, Bases, Jessica, Jose, Geraldine San, Jackson, Emily R., Dowd, Cynthia S., Couch, Robin D.
Argitaratua 2014