The effect of chain length and unsaturation on Mtb Dxr inhibition and antitubercular killing activity of FR900098 analogs

Por Jackson, Emily R., Jose, Géraldine San, Brothers, Robert C., Edelstein, Emma K., Sheldon, Zachary, Haymond, Amanda, Johny, Chinchu, Boshoff, Helena I., Couch, Robin D., Dowd, Cynthia S.
Publicado em 2013

Design of Potential Bisubstrate Inhibitors against Mycobacterium tuberculosis (Mtb) 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (Dxr)—Evidence of a Novel Binding Mode

Por San Jose, Géraldine, Jackson, Emily R., Uh, Eugene, Johny, Chinchu, Haymond, Amanda, Lundberg, Lindsay, Pinkham, Chelsea, Kehn-Hall, Kylene, Boshoff, Helena I., Couch, Robin D., Dowd, Cynthia S.
Publicado em 2013

Kinetic Characterization and Allosteric Inhibition of the Yersinia pestis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (MEP Synthase)

Por Haymond, Amanda, Johny, Chinchu, Dowdy, Tyrone, Schweibenz, Brandon, Villarroel, Karen, Young, Richard, Mantooth, Clark J., Patel, Trishal, Bases, Jessica, Jose, Geraldine San, Jackson, Emily R., Dowd, Cynthia S., Couch, Robin D.
Publicado em 2014

Structure-Activity Relationships of the MEPicides: N-acyl and O-linked Analogs of FR900098 as Inhibitors of Dxr from Mycobacterium tuberculosis and Yersinia pestis

Por San Jose, Géraldine, Jackson, Emily R., Haymond, Amanda, Johny, Chinchu, Edwards, Rachel L., Wang, Xu, Brothers, R. Carl, Edelstein, Emma K., Odom, Audrey R., Boshoff, Helena I., Couch, Robin D., Dowd, Cynthia S.
Publicado no ACS Infect Dis (2016)