Mycobacterium leprae Is Naturally Resistant to PA-824

Leprosy responds very slowly to the current multidrug therapy, and hence there is a need for novel drugs with potent bactericidal activity. PA-824 is a 4-nitroimidazo-oxazine that is currently undergoing phase I clinical trials for the treatment of tuberculosis. The activity of PA-824 against Mycoba...

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Bibliografske podrobnosti
Main Authors: Manjunatha, Ujjini H., Lahiri, Ramanuj, Randhawa, Baljit, Dowd, Cynthia S., Krahenbuhl, James L., Barry, Clifton E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610092/
https://ncbi.nlm.nih.gov/pubmed/17005816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00488-06
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