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Phosphonate prodrugs: an overview and recent advances
Phosphonates, often used as isosteric replacements for phosphates, can provide important interactions with an enzyme. Due to their high charge at physiological pH, however, permeation into cells can be a challenge. Protecting phosphonates as prodrugs has shown promise in drug delivery. Thus, a varie...
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| Publicat a: | Future Med Chem |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Newlands Press Ltd
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6722485/ https://ncbi.nlm.nih.gov/pubmed/31469328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0591 |
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