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Phosphonate prodrugs: an overview and recent advances

Phosphonates, often used as isosteric replacements for phosphates, can provide important interactions with an enzyme. Due to their high charge at physiological pH, however, permeation into cells can be a challenge. Protecting phosphonates as prodrugs has shown promise in drug delivery. Thus, a varie...

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Detaylı Bibliyografya
Yayımlandı:Future Med Chem
Asıl Yazarlar: Heidel, Kenneth M, Dowd, Cynthia S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Newlands Press Ltd 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722485/
https://ncbi.nlm.nih.gov/pubmed/31469328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0591
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