Efficient diastereoselective synthesis of a new class of azanucleosides: 2′-homoazanucleosides

Por Bouton, Jakob, Van Hecke, Kristof, Van Calenbergh, Serge
Publicado no Tetrahedron (2017)

Synthesis of pyrrolidine-based hamamelitannin analogues as quorum sensing inhibitors in Staphylococcus aureus

Por Bouton, Jakob, Van Hecke, Kristof, Rasooly, Reuven, Van Calenbergh, Serge
Publicado no Beilstein J Org Chem (2018)

Acyloxybenzyl and Alkoxyalkyl Prodrugs of a Fosmidomycin Surrogate as Antimalarial and Antitubercular Agents

Por Courtens, Charlotte, Risseeuw, Martijn, Caljon, Guy, Cos, Paul, Van Calenbergh, Serge
Publicado no ACS Med Chem Lett (2018)

Structural basis of NKT cell inhibition using the T-cell receptor-blocking anti-CD1d antibody 1B1

Por Ying, Ge, Wang, Jing, Mallevaey, Thierry, Van Calenbergh, Serge, Zajonc, Dirk M.
Publicado no J Biol Chem (2019)

Exploring the purine core of 3′-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics

Por Hulpia, Fabian, Balzarini, Jan, Schols, Dominique, Andrei, Graciela, Snoeck, Robert, Van Calenbergh, Serge
Publicado no Bioorg Med Chem Lett (2016)

Exploring human adenosine A(3) receptor complementarity and activity for adenosine analogues modified in the ribose and purine moiety

Por Van Rompaey, Philippe, Jacobson, Kenneth A., Gross, Ariel S., Gao, Zhan-Guo, Van Calenbergh, Serge
Publicado em 2005

Synthesis of C-5″ and C-6″-modified α-GalCer analogues as iNKT-cell agonists

Por Guillaume, Joren, Pauwels, Nora, Aspeslagh, Sandrine, Zajonc, Dirk M., Elewaut, Dirk, Van Calenbergh, Serge
Publicado no Bioorg Med Chem (2015)

Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR

Por Brackman, Gilles, Defoirdt, Tom, Miyamoto, Carol, Bossier, Peter, Van Calenbergh, Serge, Nelis, Hans, Coenye, Tom
Publicado em 2008

Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A’ Pocket Unable to Bind Long-Chain Glycolipids

Por Wang, Jing, Guillaume, Joren, Pauwels, Nora, Van Calenbergh, Serge, Van Rhijn, Ildiko, Zajonc, Dirk M.
Publicado em 2012

Synthesis and Evaluation of N(6)-Substituted Apioadenosines as Potential Adenosine A(3) Receptor Modulators

Por Toti, Kiran S., Moss, Steven M., Paoletta, Silvia, Gao, Zhan-Guo, Jacobson, Kenneth A., Van Calenbergh, Serge
Publicado em 2014

Synthesis and structure-activity relationships of cerebroside analogues as substrates of cerebroside sulphotransferase and discovery of a competitive inhibitor

Por Li, Wenjin, Guillaume, Joren, Baqi, Younis, Wachsmann, Isabell, Gieselmann, Volkmar, Van Calenbergh, Serge, Müller, Christa E.
Publicado no J Enzyme Inhib Med Chem (2020)

Novel Potentiators for Vancomycin in the Treatment of Biofilm-Related MRSA Infections via a Mix and Match Approach

Por Vermote, Arno, Brackman, Gilles, Risseeuw, Martijn D. P., Cappoen, Davie, Cos, Paul, Coenye, Tom, Van Calenbergh, Serge
Publicado no ACS Med Chem Lett (2016)

Synthesis of a 3′-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides

Por Hulpia, Fabian, Noppen, Sam, Schols, Dominique, Andrei, Graciela, Snoeck, Robert, Liekens, Sandra, Vervaeke, Peter, Van Calenbergh, Serge
Publicado no Eur J Med Chem (2018)

Synthesis and P2Y Receptor Activity of Nucleoside 5′-Phosphonate Derivatives

Por Cosyn, Liesbet, Van Calenbergh, Serge, Joshi, Bhalchandra V., Ko, Hyojin, Carter, Rhonda L., Harden, T. Kendall, Jacobson, Kenneth A.
Publicado em 2009

Synthesis and Evaluation of Amino-Modified α-GalCer Analogues

Por Trappeniers, Matthias, Chofor, René, Aspeslagh, Sandrine, Li, Yali, Linclau, Bruno, Zajonc, Dirk M., Elewaut, Dirk, Van Calenbergh, Serge
Publicado em 2010

Structure-Activity Relationship of Cinnamaldehyde Analogs as Inhibitors of AI-2 Based Quorum Sensing and Their Effect on Virulence of Vibrio spp

Por Brackman, Gilles, Celen, Shari, Hillaert, Ulrik, Van Calenbergh, Serge, Cos, Paul, Maes, Louis, Nelis, Hans J., Coenye, Tom
Publicado em 2011

Design, Synthesis and Characterization of a New Series of Fluorescent Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulators

Por Fernández-Dueñas, Víctor, Qian, Mingcheng, Argerich, Josep, Amaral, Carolina, Risseeuw, Martijn D.P., Van Calenbergh, Serge, Ciruela, Francisco
Publicado no Molecules (2020)

The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release

Por Brackman, Gilles, Breyne, Koen, De Rycke, Riet, Vermote, Arno, Van Nieuwerburgh, Filip, Meyer, Evelyne, Van Calenbergh, Serge, Coenye, Tom
Publicado no Sci Rep (2016)

2-Triazole-Substituted Adenosines: A New Class of Selective A(3) Adenosine Receptor Agonists, Partial Agonists, and Antagonists

Por Cosyn, Liesbet, Palaniappan, Krishnan K., Kim, Soo-Kyung, Duong, Heng T., Gao, Zhan-Guo, Jacobson, Kenneth A., Van Calenbergh, Serge
Publicado no J Med Chem (2006)

Synthesis of Extended Uridine Phosphonates Derived from an Allosteric P2Y(2) Receptor Ligand

Por Song, Lijun, Risseeuw, Martijn D. P., Karalic, Izet, Barrett, Matthew O., Brown, Kyle A., Harden, T. Kendall, Van Calenbergh, Serge
Publicado no Molecules (2014)