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Exploring human adenosine A(3) receptor complementarity and activity for adenosine analogues modified in the ribose and purine moiety

In this paper we investigated the influence on affinity, selectivity and intrinsic activity upon modification of the adenosine agonist scaffold at the 3′- and 5′-positions of the ribofuranosyl moiety and the 2- and N(6)-positions of the purine base. This resulted in the synthesis of various analogue...

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Detaylı Bibliyografya
Asıl Yazarlar: Van Rompaey, Philippe, Jacobson, Kenneth A., Gross, Ariel S., Gao, Zhan-Guo, Van Calenbergh, Serge
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460517/
https://ncbi.nlm.nih.gov/pubmed/15670905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2004.11.044
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