Search for New Purine- and Ribose-Modified Adenosine Analogues as Selective Agonists and Antagonists at Adenosine Receptors()

The binding affinities at rat A(1), A(2a), and A(3) adenosine receptors of a wide range of derivatives of adenosine have been determined. Sites of modification include the purine moiety (1-, 3-, and 7-deaza; halo, alkyne, and amino substitutions at the 2- and 8-positions; and N(6)-CH(2)-ring, -hydra...

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Detalhes bibliográficos
Main Authors: Siddiqi, Suhaib M., Jacobson, Kenneth A., Esker, John L., Olah, Mark E., Ji, Xiao-duo, Melman, Neli, Tiwari, Kamal N., Secrist, John A., Schneller, Stewart W., Cristalli, Gloria, Stiles, Gary L., Johnson, Carl R., IJzerman, Ad P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457658/
https://ncbi.nlm.nih.gov/pubmed/7707320
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