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Structural determinants of efficacy at A(3) adenosine receptors: modification of the ribose moiety

We have found previously that structural features of adenosine derivatives, particularly at the N(6)- and 2-positions of adenine, determine the intrinsic efficacy as A(3) adenosine receptor (AR) agonists. Here, we have probed this phenomenon with respect to the ribose moiety using a series of ribose...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Gao, Zhan-Guo, Jeong, Lak Shin, Moon, Hyung Ryong, Kim, Hea Ok, Choi, Won Jun, Shin, Dae Hong, Elhalem, Eleonora, Comin, Maria J., Melman, Neli, Mamedova, Liaman, Gross, Ariel S., Rodriguez, Juan B., Jacobson, Kenneth A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150582/
https://ncbi.nlm.nih.gov/pubmed/15104242
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