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Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR

BACKGROUND: To date, only few compounds targeting the AI-2 based quorum sensing (QS) system are known. In the present study, we screened cinnamaldehyde and substituted cinnamaldehydes for their ability to interfere with AI-2 based QS. The mechanism of QS inhibition was elucidated by measuring the ef...

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Autors principals: Brackman, Gilles, Defoirdt, Tom, Miyamoto, Carol, Bossier, Peter, Van Calenbergh, Serge, Nelis, Hans, Coenye, Tom
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551610/
https://ncbi.nlm.nih.gov/pubmed/18793453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-8-149
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