Synthesis and Evaluation of Amino-Modified α-GalCer Analogues

[Image: see text] α-GalCer analogues featuring a phytoceramide 3- and 4-amino group have been synthesized. A Mitsunobu reaction involving phthalimide was employed for the introduction of the amino groups at the 3- and 4-positions of suitable phytosphingosine-derived precursors. The influence of thes...

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Bibliografiske detaljer
Main Authors: Trappeniers, Matthias, Chofor, René, Aspeslagh, Sandrine, Li, Yali, Linclau, Bruno, Zajonc, Dirk M., Elewaut, Dirk, Van Calenbergh, Serge
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903208/
https://ncbi.nlm.nih.gov/pubmed/20518554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100934z
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