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Synthesis and Evaluation of Amino-Modified α-GalCer Analogues
[Image: see text] α-GalCer analogues featuring a phytoceramide 3- and 4-amino group have been synthesized. A Mitsunobu reaction involving phthalimide was employed for the introduction of the amino groups at the 3- and 4-positions of suitable phytosphingosine-derived precursors. The influence of thes...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903208/ https://ncbi.nlm.nih.gov/pubmed/20518554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100934z |
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