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Novel Potentiators for Vancomycin in the Treatment of Biofilm-Related MRSA Infections via a Mix and Match Approach

[Image: see text] A library of 52 hamamelitannin analogues was synthesized and investigated for its ability to potentiate the effect of vancomycin toward Staphylococcus aureus biofilms. Several compounds were found to effectively increase the susceptibility of staphylococcal biofilms toward this gly...

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Publicado en:ACS Med Chem Lett
Autores principales: Vermote, Arno, Brackman, Gilles, Risseeuw, Martijn D. P., Cappoen, Davie, Cos, Paul, Coenye, Tom, Van Calenbergh, Serge
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2016
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238489/
https://ncbi.nlm.nih.gov/pubmed/28105272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00315
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