Novel Potentiators for Vancomycin in the Treatment of Biofilm-Related MRSA Infections via a Mix and Match Approach

[Image: see text] A library of 52 hamamelitannin analogues was synthesized and investigated for its ability to potentiate the effect of vancomycin toward Staphylococcus aureus biofilms. Several compounds were found to effectively increase the susceptibility of staphylococcal biofilms toward this gly...

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Vydáno v:ACS Med Chem Lett
Hlavní autoři: Vermote, Arno, Brackman, Gilles, Risseeuw, Martijn D. P., Cappoen, Davie, Cos, Paul, Coenye, Tom, Van Calenbergh, Serge
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2016
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238489/
https://ncbi.nlm.nih.gov/pubmed/28105272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00315
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