Pitfalls associated with evaluating enzymatic quorum quenching activity: the case of MomL and its effect on Pseudomonas aeruginosa and Acinetobacter baumannii biofilms

BACKGROUND: The enzymatic degradation of quorums sensing (QS) molecules (called quorum quenching, QQ) has been considered as a promising anti-virulence therapy to treat biofilm-related infections and combat antibiotic resistance. The recently-discovered QQ enzyme MomL has been reported to efficientl...

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Vydáno v:PeerJ
Hlavní autoři: Zhang, Yunhui, Brackman, Gilles, Coenye, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: PeerJ Inc. 2017
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410158/
https://ncbi.nlm.nih.gov/pubmed/28462048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3251
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