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The Tyrosine Kinase Pyk2 Promotes Migration and Invasion of Glioma Cells

Glioblastoma multiforme is extraordinarily aggressive due to the propensity of cells to migrate away from the tumor core into the surrounding normal brain. In this report, we investigated the role of proline-rich tyrosine kinase 2 (Pyk2) and FAK with regard to influencing glioma cell phenotypes. Exp...

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Autori principali: Lipinski, Christopher A, Tran, Nhan L, Menashi, Emmanuel, Rohl, Carole, Kloss, Jean, Bay, R Curtis, Berens, Michael E, Loftus, Joseph C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501165/
https://ncbi.nlm.nih.gov/pubmed/15967096
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