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Structural Conservation in Band 4.1, Ezrin, Radixin, Moesin (FERM) Domains as a Guide To Identify Inhibitors of the Proline-Rich Tyrosine Kinase 2
The nonreceptor focal adhesion kinases FAK and Pyk2 play a central role in the regulation of glioma cell proliferation and migration, making them attractive targets to improve clinical outcome. Noncatalytic targeting represents a novel approach to regulate the activity of these tyrosine kinases. A c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3178892/ https://ncbi.nlm.nih.gov/pubmed/20017492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901247a |
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