Estrogen Receptor Mutations Found in Breast Cancer Metastases Integrated With the Molecular Pharmacology of Selective ER Modulators

av Jordan, V. Craig, Curpan, Ramona, Maximov, Philipp Y.
I publikationen J Natl Cancer Inst (2015)

Defining the Conformation of the Estrogen Receptor Complex That Controls Estrogen-Induced Apoptosis in Breast Cancer

av Obiorah, Ifeyinwa, Sengupta, Surojeet, Curpan, Ramona, Jordan, V. Craig
Publicerad 2014

Structural determinants of the alpha2 adrenoceptor subtype selectivity

av Ostopovici-Halip, Liliana, Curpăn, Ramona, Mracec, Maria, Bologa, Cristian G.
Publicerad 2011

CHEMICAL AND BIOLOGICAL DESCRIPTOR INTEGRATION IMPROVES COMPUTATIONAL MODELING OF IN VIVO RAT TOXICITY

av BOLOGA, Cristian G., URSU, Oleg, HALIP, Liliana, CURPĂN, Ramona, OPREA, Tudor I.
I publikationen Rev Roum Chim (2015)

The Molecular, Cellular and Clinical Consequences of Targeting the Estrogen Receptor Following Estrogen Deprivation Therapy

av Fan, Ping, Maximov, Philipp Y., Curpan, Ramona F., Abderrahman, Balkees, Jordan, V. Craig
I publikationen Mol Cell Endocrinol (2015)

Structure Function Relationships of Estrogenic Triphenylethylenes Related to Endoxifen and 4-Hydroxytamoxifen

av Maximov, Philipp Y., Myers, Cynthia, Curpan, Ramona F., Lewis-Wambi, Joan S., Jordan, V. Craig
Publicerad 2010

The Selective Estrogen Receptor Modulator Bazedoxifene Inhibits Hormone-Independent Breast Cancer Cell Growth and Down-Regulates Estrogen Receptor α and Cyclin D1

av Lewis-Wambi, Joan S., Kim, Helen, Curpan, Ramona, Grigg, Ronald, Sarker, Mohammed A., Jordan, V. Craig
Publicerad 2011

The Conformation of the Estrogen Receptor Directs Estrogen-Induced Apoptosis in Breast Cancer: A Hypothesis

av Maximov, Philipp, Sengupta, Surojeet, Lewis-Wambi, Joan S., Kim, Helen R., Curpan, Ramona F., Jordan, V Craig
Publicerad 2011

A unifying biology of sex steroid-induced apoptosis in prostate and breast cancers

av Maximov, Philipp Y, Abderrahman, Balkees, Curpan, Ramona F, Hawsawi, Yousef M, Fan, Ping, Jordan, V Craig
I publikationen Endocr Relat Cancer (2017)

Influence of the Length and Positioning of the Antiestrogenic Side Chain of Endoxifen and 4-Hydroxytamoxifen on Gene Activation and Growth of Estrogen Receptor Positive Cancer Cell...

av Maximov, Philipp Y., Fernandes, Daphne J., McDaniel, Russell E., Myers, Cynthia B., Curpan, Ramona F., Jordan, V. Craig
Publicerad 2014

Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs

av Burai, Ritwik, Ramesh, Chinnasamy, Shorty, Marvin, Curpan, Ramona, Bologa, Cristian, Sklar, Larry A., Oprea, Tudor, Prossnitz, Eric R., Arterburn, Jeffrey B.
Publicerad 2010

Pharmacological Relevance of Endoxifen in a Laboratory Simulation of Breast Cancer in Postmenopausal Patients

av Maximov, Philipp Y., McDaniel, Russell E., Fernandes, Daphne J., Bhatta, Puspanjali, Korostyshevskiy, Valeriy R., Curpan, Ramona F., Jordan, V. Craig
I publikationen J Natl Cancer Inst (2014)

Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer

av Abderrahman, Balkees, Maximov, Philipp Y., Curpan, Ramona F., Hanspal, Jay S., Fan, Ping, Xiong, Rui, Tonetti, Debra A., Thatcher, Gregory R.J., Jordan, V. Craig
I publikationen Mol Pharmacol (2020)

ChemProt: a disease chemical biology database

av Taboureau, Olivier, Nielsen, Sonny Kim, Audouze, Karine, Weinhold, Nils, Edsgärd, Daniel, Roque, Francisco S., Kouskoumvekaki, Irene, Bora, Alina, Curpan, Ramona, Jensen, Thomas Skøt, Brunak, Søren, Oprea, Tudor I.
Publicerad 2011

Detection of Intracellular Granularity Induction in Prostate Cancer Cell Lines by Small Molecules Using the HyperCyt(®) High-Throughput Flow Cytometry System

av HAYNES, MARK K., STROUSE, J. JACOB, WALLER, ANNA, LEITAO, ANDREI, CURPAN, RAMONA F., BOLOGA, CRISTIAN, OPREA, TUDOR I., PROSSNITZ, ERIC R., EDWARDS, BRUCE S., SKLAR, LARRY A., THOMPSON, TODD A.
Publicerad 2009

Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer

av Maximov, Philipp Y., Abderrahman, Balkees, Fanning, Sean W., Sengupta, Surojeet, Fan, Ping, Curpan, Ramona F., Rincon, Daniela Maria Quintana, Greenland, Jeffery A., Rajan, Shyamala S., Greene, Geoffrey L., Jordan, V. Craig
I publikationen Mol Pharmacol (2018)

High-Throughput Screen for the Chemical Inhibitors of Antiapoptotic Bcl-2 Family Proteins by Multiplex Flow Cytometry

av Curpan, Ramona F., Simons, Peter C., Zhai, Dayong, Young, Susan M., Carter, Mark B., Bologa, Cristian G., Oprea, Tudor I., Satterthwait, Arnold C., Reed, John C., Edwards, Bruce S., Sklar, Larry A.
Publicerad 2011

DrugCentral 2021 supports drug discovery and repositioning

av Avram, Sorin, Bologa, Cristian G, Holmes, Jayme, Bocci, Giovanni, Wilson, Thomas B, Nguyen, Dac-Trung, Curpan, Ramona, Halip, Liliana, Bora, Alina, Yang, Jeremy J, Knockel, Jeffrey, Sirimulla, Suman, Ursu, Oleg, Oprea, Tudor I
I publikationen Nucleic Acids Res (2020)

Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer

av Abderrahman, Balkees, Maximov, Philipp Y., Curpan, Ramona F., Fanning, Sean W., Hanspal, Jay S., Fan, Ping, Foulds, Charles E., Chen, Yue, Malovannaya, Anna, Jain, Antrix, Xiong, Rui, Greene, Geoffrey L., Tonetti, Debra A., Thatcher, Gregory R. J., Jordan, V. Craig
I publikationen Mol Cancer Ther (2020)

A Crowdsourcing Evaluation of the NIH Chemical Probes

av Oprea, Tudor I., Bologa, Cristian G., Boyer, Scott, Curpan, Ramona F., Glen, Robert C., Hopkins, Andrew L., Lipinski, Christopher A., Marshall, Garland R., Martin, Yvonne C., Ostopovici-Halip, Liliana, Rishton, Gilbert, Ursu, Oleg, Vaz, Roy J., Waller, Chris, Waldmann, Herbert, Sklar, Larry A.
Publicerad 2009