GPER-targeted, (99m)Tc-labeled, nonsteroidal ligands demonstrate selective tumor imaging and in vivo estrogen binding

Por Nayak, Tapan K., Ramesh, Chinnasamy, Hathaway, Helen J., Norenberg, Jeffrey P., Arterburn, Jeffrey B., Prossnitz, Eric R.
Publicado no Mol Cancer Res (2014)

Synthesis and Characterization of Tricarbonyl-Re/Tc(I) Chelate Probes Targeting the G Protein-Coupled Estrogen Receptor GPER/GPR30

Por Burai, Ritwik, Ramesh, Chinnasamy, Nayak, Tapan K., Dennis, Megan K., Bryant, Bj K., Prossnitz, Eric R., Arterburn, Jeffrey B.
Publicado em 2012

Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs

Por Burai, Ritwik, Ramesh, Chinnasamy, Shorty, Marvin, Curpan, Ramona, Bologa, Cristian, Sklar, Larry A., Oprea, Tudor, Prossnitz, Eric R., Arterburn, Jeffrey B.
Publicado em 2010

Pre-clinical development of a neutral, estrogen receptor-targeted, tridentate (99m)Tc(I) estradiol pyridin-2-yl hydrazine derivative for imaging of breast and endometrial cancers

Por Nayak, Tapan K., Hathaway, Helen J., Ramesh, Chinnasamy, Arterburn, Jeffrey B., Dai, Donghai, Sklar, Larry A., Norenberg, Jeffrey P., Prossnitz, Eric R.
Publicado em 2008

Synthesis and Characterization of Iodinated Tetrahydroquinolines Targeting the G Protein-coupled Estrogen Receptor GPR30

Por Ramesh, Chinnasamy, Nayak, Tapan K., Burai, Ritwik, Dennis, Megan K., Hathaway, Helen J., Sklar, Larry A., Prossnitz, Eric R., Arterburn, Jeffrey B.
Publicado em 2010

Design and Synthesis of a New Class of Membrane Permeable Triazaborolopyridinium Fluorescent Probes

Por Hapuarachchige, Sudath, Montaño, Gilbert, Ramesh, Chinnasamy, Rodriguez, Delany, Henson, Lauren H., Williams, Casey C., Kadavakkollu, Samuel, Johnson, Dennis L., Shuster, Charles B., Arterburn, Jeffrey B.
Publicado em 2011

G Protein-coupled Estrogen Receptor Protects from Atherosclerosis

Por Meyer, Matthias R., Fredette, Natalie C., Howard, Tamara A., Hu, Chelin, Ramesh, Chinnasamy, Daniel, Christoph, Amann, Kerstin, Arterburn, Jeffrey B., Barton, Matthias, Prossnitz, Eric R.
Publicado no Sci Rep (2014)

Erratum: G Protein-coupled Estrogen Receptor Protects from Atherosclerosis

Por Meyer, Matthias R., Fredette, Natalie C., Howard, Tamara A., Hu, Chelin, Ramesh, Chinnasamy, Daniel, Christoph, Amann, Kerstin, Arterburn, Jeffrey B., Barton, Matthias, Prossnitz, Eric R.
Publicado no Sci Rep (2015)

Influence of charge on cell permeability and tumor imaging of GPR30-targeted (111)In-labeled non-steroidal imaging agents

Por Nayak, Tapan K., Dennis, Megan K., Ramesh, Chinnasamy, Burai, Ritwik, Atcher, Robert W., Sklar, Larry A., Norenberg, Jeffrey P., Hathaway, Helen J., Arterburn, Jeffrey B., Prossnitz, Eric R.
Publicado em 2010

Linkage effects on binding affinity and activation of GPR30 and estrogen receptors ERα/β with tridentate pyridin-2-yl hydrazine tricarbonyl-Re/(99m)Tc(I) chelates

Por Ramesh, Chinnasamy, Bryant, Bj, Nayak, Tapan, Revankar, Chetana M., Anderson, Tamara, Carlson, Kathryn E., Katzenellenbogen, John A., Sklar, Larry A., Norenberg, Jeffrey P., Prossnitz, Eric R., Arterburn, Jeffrey B.
Publicado em 2006

Synthesis and characterization of tritylthioethanamine derivatives with potent KSP inhibitory activity

Por Rodriguez, Delany, Ramesh, Chinnasamy, Henson, Lauren H., Wilmeth, Lori, Bryant, Bj K., Kadavakollu, Samuel, Hirsch, Rebecca, Montoya, Johnelle, Howell, Porsha R., George, Jon M., Alexander, David, Johnson, Dennis L., Arterburn, Jeffrey B., Shuster, Charles B.
Publicado em 2011

Identification of a GPER/GPR30 Antagonist with Improved Estrogen Receptor Counterselectivity

Por Dennis, Megan K., Field, Angela S., Burai, Ritwik, Ramesh, Chinnasamy, Petrie, Whitney K., Bologa, Cristian G., Oprea, Tudor I., Yamaguchi, Yuri, Hayashi, Shin-ichi, Sklar, S. Larry A., Hathaway, Helen J., Arterburn, Jeffrey B., Prossnitz, Eric R.
Publicado em 2011

In vivo Effects of a GPR30 Antagonist

Por Dennis, Megan K., Burai, Ritwik, Ramesh, Chinnasamy, Petrie, Whitney K., Alcon, Sara N., Nayak, Tapan K., Bologa, Cristian G., Leitao, Andrei, Brailoiu, Eugen, Deliu, Elena, Dun, Nae J., Sklar, Larry A., Hathaway, Helen J., Arterburn, Jeffrey B., Oprea, Tudor I., Prossnitz, Eric R.
Publicado em 2009