What have we learned about GPER function in physiology and disease from knockout mice?

von Prossnitz, Eric R., Hathaway, Helen J.
Veröffentlicht in J Steroid Biochem Mol Biol (2015)

Microenvironmental control of the breast cancer cell cycle

von Guo, Xun, Wu, Yuehan, Hathaway, Helen J., Hartley, Rebecca S.
Veröffentlicht 2012

GPER Mediates Estrogen-Induced Signaling and Proliferation in Human Breast Epithelial Cells and Normal and Malignant Breast

von Scaling, Allison L., Prossnitz, Eric R., Hathaway, Helen J.
Veröffentlicht 2014

Three-dimensional collagen represses cyclin E1 via beta one integrin in invasive breast cancer cells

von Wu, Yuehan, Guo, Xun, Brandt, Yekaterina, Hathaway, Helen J., Hartley, Rebecca S.
Veröffentlicht 2010

G protein-coupled estrogen receptor (GPER) regulates mammary tumorigenesis and metastasis

von Marjon, Nicole A., Hu, Chelin, Hathaway, Helen J., Prossnitz, Eric R.
Veröffentlicht in Mol Cancer Res (2014)

Introduction of D-Phenylalanine enhanced the receptor binding affinities of gonadotropin-releasing hormone peptides

von Lu, Jie, Hathaway, Helen J., Royce, Melanie E., Prossnitz, Eric R., Miao, Yubin
Veröffentlicht 2014

GPER Deficiency in Male Mice Results in Insulin Resistance, Dyslipidemia, and a Proinflammatory State

von Sharma, Geetanjali, Hu, Chelin, Brigman, Jonathan L., Zhu, Gang, Hathaway, Helen J., Prossnitz, Eric R.
Veröffentlicht 2013

GPER-targeted, (99m)Tc-labeled, nonsteroidal ligands demonstrate selective tumor imaging and in vivo estrogen binding

von Nayak, Tapan K., Ramesh, Chinnasamy, Hathaway, Helen J., Norenberg, Jeffrey P., Arterburn, Jeffrey B., Prossnitz, Eric R.
Veröffentlicht in Mol Cancer Res (2014)

Sex Differences in Murine Myocutaneous Flap Revascularization

von Brandenburg, Jacquelyn S., Clark, Ross M., Coffman, Brittany, Sharma, Geetanjali, Hathaway, Helen J., Prossnitz, Eric R., Howdieshell, Thomas R.
Veröffentlicht in Wound Repair Regen (2020)

Pre-clinical development of a neutral, estrogen receptor-targeted, tridentate (99m)Tc(I) estradiol pyridin-2-yl hydrazine derivative for imaging of breast and endometrial cancers

von Nayak, Tapan K., Hathaway, Helen J., Ramesh, Chinnasamy, Arterburn, Jeffrey B., Dai, Donghai, Sklar, Larry A., Norenberg, Jeffrey P., Prossnitz, Eric R.
Veröffentlicht 2008

Synthesis and Characterization of Iodinated Tetrahydroquinolines Targeting the G Protein-coupled Estrogen Receptor GPR30

von Ramesh, Chinnasamy, Nayak, Tapan K., Burai, Ritwik, Dennis, Megan K., Hathaway, Helen J., Sklar, Larry A., Prossnitz, Eric R., Arterburn, Jeffrey B.
Veröffentlicht 2010

G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth

von Petrie, Whitney K., Dennis, Megan K., Hu, Chelin, Dai, Donghai, Arterburn, Jeffrey B., Smith, Harriet O., Hathaway, Helen J., Prossnitz, Eric R.
Veröffentlicht 2013

Complement Receptor 3 contributes to the sexual dimorphism in neutrophil killing of Staphylococcus aureus

von Pokhrel, Srijana, Triplett, Kathleen D., Daly, Seth M., Joyner, Jason A., Sharma, Geetanjali, Hathaway, Helen J., Prossnitz, Eric R., Hall, Pamela R.
Veröffentlicht in J Immunol (2020)

DELETION OF G PROTEIN-COUPLED ESTROGEN RECEPTOR INCREASES ENDOTHELIAL VASOCONSTRICTION

von Meyer, Matthias R., Amann, Kerstin, Field, Angela S., Hu, Chelin, Hathaway, Helen J., Kanagy, Nancy L., Walker, Mary K., Barton, Matthias, Prossnitz, Eric R.
Veröffentlicht 2011

The R-Enantiomer of Ketorolac Delays Mammary Tumor Development in Mouse Mammary Tumor Virus-Polyoma Middle T Antigen (MMTV-PyMT) Mice

von Peretti, Amanda S., Dominguez, Dayna, Grimes, Martha M., Hathaway, Helen J., Prossnitz, Eric R., Rivera, Melanie R., Wandinger-Ness, Angela, Kusewitt, Donna F., Hudson, Laurie G.
Veröffentlicht in Am J Pathol (2018)

Influence of charge on cell permeability and tumor imaging of GPR30-targeted (111)In-labeled non-steroidal imaging agents

von Nayak, Tapan K., Dennis, Megan K., Ramesh, Chinnasamy, Burai, Ritwik, Atcher, Robert W., Sklar, Larry A., Norenberg, Jeffrey P., Hathaway, Helen J., Arterburn, Jeffrey B., Prossnitz, Eric R.
Veröffentlicht 2010

Preclinical efficacy of the first-in-class GPER-selective agonist G-1 in mouse models of obesity and diabetes

von Sharma, Geetanjali, Hu, Chelin, Staquicini, Daniela I., Brigman, Jonathan L., Liu, Meilian, Mauvais-Jarvis, Franck, Pasqualini, Renata, Arap, Wadih, Arterburn, Jeffrey B., Hathaway, Helen J., Prossnitz, Eric R.
Veröffentlicht in Sci Transl Med (2020)

Enhanced leukemia cell detection using a novel magnetic needle and nanoparticles

von Jaetao, Jason E., Butler, Kimberly S., Adolphi, Natalie L., Lovato, Debbie M., Bryant, Howard C., Rabinowitz, Ian, Winter, Stuart S., Tessier, Trace E., Hathaway, Helen J., Bergemann, Christian, Flynn, Edward R., Larson, Richard S.
Veröffentlicht 2009

Innate Sex Bias of Staphylococcus aureus Skin Infection is Driven by alpha-Hemolysin

von Castleman, Moriah J., Pokhrel, Srijana, Triplett, Kathleen D., Kusewitt, Donna F., Elmore, Bradley O., Joyner, Jason A., Femling, Jon K., Sharma, Geetanjali, Hathaway, Helen J., Prossnitz, Eric R., Hall, Pamela R.
Veröffentlicht in J Immunol (2017)

GPER activation protects against epithelial barrier disruption by Staphylococcusaureus α-toxin

von Triplett, Kathleen D., Pokhrel, Srijana, Castleman, Moriah J., Daly, Seth M., Elmore, Bradley O., Joyner, Jason A., Sharma, Geetanjali, Herbert, Guy, Campen, Matthew J., Hathaway, Helen J., Prossnitz, Eric R., Hall, Pamela R.
Veröffentlicht in Sci Rep (2019)