GPER activation protects against epithelial barrier disruption by Staphylococcusaureus α-toxin

Sex bias in innate defense against Staphylococcus aureus skin and soft tissue infection (SSTI) is dependent on both estrogen production by the host and S. aureus secretion of the virulence factor, α-hemolysin (Hla). The impact of estrogen signaling on the immune system is most often studied in terms...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Triplett, Kathleen D., Pokhrel, Srijana, Castleman, Moriah J., Daly, Seth M., Elmore, Bradley O., Joyner, Jason A., Sharma, Geetanjali, Herbert, Guy, Campen, Matthew J., Hathaway, Helen J., Prossnitz, Eric R., Hall, Pamela R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362070/
https://ncbi.nlm.nih.gov/pubmed/30718654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37951-3
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