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G protein-coupled estrogen receptor (GPER) regulates mammary tumorigenesis and metastasis

The role of 17β-estradiol (E2) in breast cancer development and tumor growth has traditionally been attributed exclusively to the activation of ERα. Although targeted inhibition of ERα is a successful approach for patients with ERα(+) breast cancer, many patients fail to respond or become resistant...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Marjon, Nicole A., Hu, Chelin, Hathaway, Helen J., Prossnitz, Eric R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233188/
https://ncbi.nlm.nih.gov/pubmed/25030371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0128-T
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