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GPER Mediates Estrogen-Induced Signaling and Proliferation in Human Breast Epithelial Cells and Normal and Malignant Breast

17β-Estradiol (estrogen), through receptor binding and activation, is required for mammary gland development. Estrogen stimulates epithelial proliferation in the mammary gland, promoting ductal elongation and morphogenesis. In addition to a developmental role, estrogen promotes proliferation in tumo...

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Detalhes bibliográficos
Main Authors: Scaling, Allison L., Prossnitz, Eric R., Hathaway, Helen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091989/
https://ncbi.nlm.nih.gov/pubmed/24718936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-014-0174-1
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