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Synthesis and Characterization of Iodinated Tetrahydroquinolines Targeting the G Protein-coupled Estrogen Receptor GPR30

A series of iodo-substituted tetrahydro-3H-cyclopenta[c]quinolines was synthesized as potential targeted imaging agents for the G protein-coupled estrogen receptor GPR30. The affinity and specificity of binding to GPR30 versus the classical estrogen receptors ERα/β and functional responses associate...

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Bibliografske podrobnosti
Main Authors: Ramesh, Chinnasamy, Nayak, Tapan K., Burai, Ritwik, Dennis, Megan K., Hathaway, Helen J., Sklar, Larry A., Prossnitz, Eric R., Arterburn, Jeffrey B.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818973/
https://ncbi.nlm.nih.gov/pubmed/20041667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9011802
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