The Conformation of the Estrogen Receptor Directs Estrogen-Induced Apoptosis in Breast Cancer: A Hypothesis

BACKGROUND: Estrogens are classified as type I (planar) and type II (angular) based on their structures. In this study we have used triphenylethylenes (TPEs) compounds related to 4OHT to address the hypothesis that the conformation of the liganded estrogen receptor (ERα) may dictate the E2-induced a...

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Bibliographic Details
Main Authors: Maximov, Philipp, Sengupta, Surojeet, Lewis-Wambi, Joan S., Kim, Helen R., Curpan, Ramona F., Jordan, V Craig
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109984/
https://ncbi.nlm.nih.gov/pubmed/21660224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/HMBCI.2010.047
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