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Structure Function Relationships of Estrogenic Triphenylethylenes Related to Endoxifen and 4-Hydroxytamoxifen

Estrogens can potentially be classified into planar (Class I) or non planar (Class II) categories, which might have biological consequences. 1,1,2-Triphenoplsylethylene (TPE) derivatives were synthesized and evaluated against 17β-estradiol (E2) for their estrogenic activity in MCF-7 human breast can...

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Autors principals: Maximov, Philipp Y., Myers, Cynthia, Curpan, Ramona F., Lewis-Wambi, Joan S., Jordan, V. Craig
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867604/
https://ncbi.nlm.nih.gov/pubmed/20334368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901907u
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