Potential Mechanisms of Estrogen Quinone Carcinogenesis

Por Bolton, Judy L., Thatcher, Gregory R.J.
Publicado em 2007

CHEMICAL MODIFICATION MODULATES ESTROGENIC ACTIVITY, OXIDATIVE REACTIVITY, & METABOLIC STABILITY IN 4′F-DMA, A NEW BENZOTHIOPHENE SELECTIVE ESTROGEN RECEPTOR MODULATOR

Por Liu, Hong, Bolton, Judy L., Thatcher, Gregory R. J.
Publicado em 2006

Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors

Por Siklos, Marton, BenAissa, Manel, Thatcher, Gregory R.J.
Publicado no Acta Pharm Sin B (2015)

UTERINE PEROXIDASE CATALYZED FORMATION OF DI-QUINONE METHIDES FROM THE SELECTIVE ESTROGEN RECEPTOR MODULATORS (SERMS) RALOXIFENE AND DESMETHYLATED ARZOXIFENE

Por Liu, Hong, Qin, Zhihui, Thatcher, Gregory R. J., Bolton, Judy L.
Publicado em 2007

Estrogen-Induced Apoptosis of Breast Epithelial Cells Is Blocked by NO/cGMP and Mediated by Extranuclear Estrogen Receptors

Por Kastrati, Irida, Edirisinghe, Praneeth D., Wijewickrama, Gihani T., Thatcher, Gregory R. J.
Publicado em 2010

Bioactivation of Selective Estrogen Receptor Modulators (SERMs)

Por Dowers, Tamara S., Qin, Zhi-Hui, Thatcher, Gregory R. J., Bolton, Judy L.
Publicado em 2006

NO-flurbiprofen reduces amyloid β, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade

Por Abdul-Hay, Samer O., Luo, Jia, Ashghodom, Rezene T., Thatcher, Gregory R.J.
Publicado em 2009

Is S-Nitrosocysteine a True Surrogate for Nitric Oxide?

Por Hickok, Jason R., Vasudevan, Divya, Thatcher, Gregory R.J., Thomas, Douglas D.
Publicado em 2012

Furoxans (1, 2, 5 Oxadiazole-N-Oxides) as Novel NO Mimetic Neuroprotective and Procognitive Agents

Por Schiefer, Isaac T., VandeVrede, Lawren, Fa', Mauro, Arancio, Ottavio, Thatcher, Gregory R. J.
Publicado em 2012

Proteomic Profiling of Nitrosative Stress: Protein S-Oxidation Accompanies S-Nitrosylation

Por Wang, Yue-Ting, Piyankarage, Sujeewa C., Williams, David L., Thatcher, Gregory R. J.
Publicado em 2014

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells

Por Kastrati, Irida, Delgado-Rivera, Loruhama, Georgieva, Gergana, Thatcher, Gregory R. J., Frasor, Jonna
Publicado no J Vis Exp (2017)

A Novel Strategy to Co-target Estrogen Receptor and Nuclear Factor κB Pathways with Hybrid Drugs for Breast Cancer Therapy

Por Kastrati, Irida, Siklos, Marton I., Brovkovych, Svitlana D., Thatcher, Gregory R. J., Frasor, Jonna
Publicado no Horm Cancer (2017)

Comparative methods for analysis of protein covalent modification by electrophilic quinoids formed from xenobiotics

Por Yu, Bolan, Qin, Zhihui, Wijewickrama, Gihani T., Edirisinghe, Praneeth, Bolton, Judy L., Thatcher, Gregory R. J.
Publicado em 2009

GT-094, a NO-NSAID, Inhibits Colon Cancer Cell Growth by Activation of a Reactive Oxygen Species (ROS)-MicroRNA-27a:ZBTB10-Specificity Protein (Sp) Pathway

Por Pathi, Satya S., Jutooru, Indira, Chadalapaka, Gayathri, Sreevalsan, Sandeep, Anand, S., Thatcher, Gregory R. J., Safe, Stephen
Publicado em 2010

Inhibition of amyloidogenesis by non-steroidal anti-inflammatory drugs and their hybrid nitrates

Por Schiefer, Isaac T., Abdul-Hay, Samer, Wang, Huali, Vanni, Michael, Qin, Zhihui, Thatcher, Gregory R. J.
Publicado em 2011

A novel aspirin prodrug inhibits NFκB activity and breast cancer stem cell properties

Por Kastrati, Irida, Litosh, Vladislav A., Zhao, Shuangping, Alvarez, Manuel, Thatcher, Gregory R. J., Frasor, Jonna
Publicado no BMC Cancer (2015)

Analysis of Protein Covalent Modification by Xenobiotics using a Covert Oxidatively Activated Tag: Raloxifene Proof-of-Principle Study

Por Liu, Ju, Li, Qian, Yang, Xiaofeng, van Breemen, Richard B., Bolton, Judy L., Thatcher, Gregory R. J.
Publicado em 2005

Development of a Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry Method for Analysis of Stable 4-Hydroxyequilenin-DNA Adducts in Human Breast Cancer Cells

Por Wang, Zhican, Edirisinghe, Praneeth, Sohn, Johann, Qin, Zhihui, Geacintov, Nicholas E., Thatcher, Gregory R. J., Bolton, Judy L.
Publicado em 2009

Proteomic and mass spectroscopic quantitation of protein S-nitrosation differentiates NO-donors

Por Sinha, Vaishali, Wijewickrama, Gihani T., Chandrasena, R. Esala P., Xu, Hua, Edirisinghe, Praneeth D., Schiefer, Isaac T., Thatcher, Gregory R. J.
Publicado em 2010

Unexpected hormonal activity of a catechol equine estrogen metabolite reveals reversible glutathione conjugation

Por Peng, Kuan-Wei, Chang, Minsun, Wang, Yue-Ting, Wang, Zhican, Qin, Zhihui, Bolton, Judy L., Thatcher, Gregory R. J.
Publicado em 2010