A novel aspirin prodrug inhibits NFκB activity and breast cancer stem cell properties

Por Kastrati, Irida, Litosh, Vladislav A., Zhao, Shuangping, Alvarez, Manuel, Thatcher, Gregory R. J., Frasor, Jonna
Publicado no BMC Cancer (2015)

Termination of DNA synthesis by N(6)-alkylated, not 3′-O-alkylated, photocleavable 2′-deoxyadenosine triphosphates

Por Wu, Weidong, Stupi, Brian P., Litosh, Vladislav A., Mansouri, Dena, Farley, Demetra, Morris, Sidney, Metzker, Sherry, Metzker, Michael L.
Publicado em 2007

Improved nucleotide selectivity and termination of 3′-OH unblocked reversible terminators by molecular tuning of 2-nitrobenzyl alkylated HOMedU triphosphates

Por Litosh, Vladislav A., Wu, Weidong, Stupi, Brian P., Wang, Jinchun, Morris, Sidney E., Hersh, Megan N., Metzker, Michael L.
Publicado em 2011

Stereochemistry of Benzylic Carbon Substitution Coupled with Ring Modification of 2-Nitrobenzyl Groups as Key Determinants for Fast-Cleaving Reversible Terminators**

Por Stupi, Brian P, Li, Hong, Wang, Jinchun, Wu, Weidong, Morris, Sidney E, Litosh, Vladislav A, Muniz, Jesse, Hersh, Megan N, Metzker, Michael L
Publicado em 2012

Eosinophilic esophagitis–linked calpain 14 is an IL-13–induced protease that mediates esophageal epithelial barrier impairment

Por Davis, Benjamin P., Stucke, Emily M., Khorki, M. Eyad, Litosh, Vladislav A., Rymer, Jeffrey K., Rochman, Mark, Travers, Jared, Kottyan, Leah C., Rothenberg, Marc E.
Publicado no JCI Insight (2016)

Benzothiophene Selective Estrogen Receptor Modulators Provide Neuroprotection by a Novel GPR30-Dependent Mechanism

Por Abdelhamid, Ramy, Luo, Jia, VandeVrede, Lawren, Kundu, Indraneel, Michalsen, Bradley, Litosh, Vladislav A., Schiefer, Isaac T., Gherezghiher, Teshome, Yao, Ping, Qin, Zhihui, Thatcher, Gregory R. J.
Publicado em 2011

Base-modified thymidines capable of terminating DNA synthesis are novel bioactive compounds with activity in cancer cells

Por Borland, Kayla M., AbdulSalam, Safnas F., Solivio, Morwena J., Burke, Matthew P., Wolfkiel, Patrick R., Lawson, Sean M., Stockman, Courtney A., Andersen, Joel M., Smith, Skyler, Tolstolutskaya, Julia N., Gurjar, Purujit N., Bercz, Aron P., Merino, Edward J., Litosh, Vladislav A.
Publicado no Bioorg Med Chem (2015)