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Benzothiophene Selective Estrogen Receptor Modulators Provide Neuroprotection by a Novel GPR30-Dependent Mechanism
[Image: see text] The clinical benzothiophene SERM (BT-SERM) raloxifene was compared with estrogens in protection of primary rat neurons against oxygen-glucose deprivation (OGD). Structure−activity relationships for neuroprotection were determined for a family of BT-SERMs displaying a spectrum of ER...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical Society
2011
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124785/ https://ncbi.nlm.nih.gov/pubmed/21731800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100106a |
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