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Comparative methods for analysis of protein covalent modification by electrophilic quinoids formed from xenobiotics
Conjugation of biotin and fluorophore tags is useful for assaying covalent protein modification. Oxidative bioactivation of selective estrogen receptor modulators (SERMs) yields reactive quinoid electrophiles that covalently modify proteins; bioactivation is associated with carcinogenic and chemopre...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827204/ https://ncbi.nlm.nih.gov/pubmed/19301905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800435m |
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