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Inhibition of amyloidogenesis by non-steroidal anti-inflammatory drugs and their hybrid nitrates
Poor blood-brain barrier penetration of non-steroidal anti-inflammatory drugs (NSAIDs) has been blamed for the failure of the selective amyloid lowering agent (SALA) R-flurbiprofen in phase 3 clinical trials for Alzheimer’s disease (AD). NO-donor NSAIDs (NO-NSAIDs) provide an alternative, gastric-sp...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072465/ https://ncbi.nlm.nih.gov/pubmed/21405086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101450p |
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