Black Swans and white tablets

Por Oprea, Tudor I, Hopkins, Andrew L
Publicado no Chem Cent J (2008)

Computational and Practical Aspects of Drug Repositioning

Por Oprea, Tudor I., Overington, John P.
Publicado no Assay Drug Dev Technol (2015)

Identification of a functional water channel in cytochrome P450 enzymes

Por Oprea, Tudor I., Hummer, Gerhard, García, Angel E.
Publicado em 1997

BDDCS Applied to Over 900 Drugs

Por Benet, Leslie Z., Broccatelli, Fabio, Oprea, Tudor I.
Publicado em 2011

Transporter-mediated Efflux Influences CNS Side Effects: ABCB1, from Antitarget to Target

Por Broccatelli, Fabio, Carosati, Emanuele, Cruciani, Gabriele, Oprea, Tudor I.
Publicado em 2010

Fitting the Complexity of GPCRs Modulation into Simple Hypotheses of Ligand Design

Por Custodi, Chiara, Nuti, Roberto, Oprea, Tudor I., Macchiarulo, Antonio
Publicado em 2012

Impact of similarity threshold on the topology of molecular similarity networks and clustering outcomes

Por Zahoránszky-Kőhalmi, Gergely, Bologa, Cristian G., Oprea, Tudor I.
Publicado no J Cheminform (2016)

iPHACE: integrative navigation in pharmacological space

Por Garcia-Serna, Ricard, Ursu, Oleg, Oprea, Tudor I., Mestres, Jordi
Publicado em 2010

BDDCS Class Prediction for New Molecular Entities

Por Broccatelli, Fabio, Cruciani, Gabriele, Benet, Leslie Z., Oprea, Tudor I.
Publicado em 2012

Computational Systems Chemical Biology

Por Oprea, Tudor I., May, Elebeoba E., Leitão, Andrei, Tropsha, Alexander
Publicado em 2011

Cross-Pharmacology Analysis of G Protein-Coupled Receptors

Por Briansó, Ferran, Carrascosa, Maria C., Oprea, Tudor I., Mestres, Jordi
Publicado em 2011

A Systems Chemical Biology Study of Malate Synthase and Isocitrate Lyase Inhibition in Mycobacterium tuberculosis During Active and NRP Growth

Por May, Elebeoba E., Leitão, Andrei, Tropsha, Alexander, Oprea, Tudor I.
Publicado em 2013

The University of New Mexico Center for Molecular Discovery

Por Edwards, Bruce S., Gouveia, Kristine, Oprea, Tudor I., Sklar, Larry A.
Publicado no Comb Chem High Throughput Screen (2014)

ACTIVATION OF DIOXIN RESPONSE ELEMENT (DRE)-ASSOCIATED GENES BY BENZO(A)PYRENE 3,6-QUINONE AND BENZO(A)PYRENE 1,6-QUINONE IN MCF-10A HUMAN MAMMARY EPITHELIAL CELLS

Por Burchiel, Scott W., Thompson, Todd A., Lauer, Fredine T., Oprea, Tudor I.
Publicado em 2007

Novel Chemical Space Exploration via Natural Products

Por Rosén, Josefin, Gottfries, Johan, Muresan, Sorel, Backlund, Anders, Oprea, Tudor I.
Publicado em 2009

Systems Chemical Biology

Por Oprea, Tudor I., Tropsha, Alexander, Faulon, Jean-Loup, Rintoul, Mark D.
Publicado em 2007

Erratum to: Impact of similarity threshold on the topology of molecular similarity networks and clustering outcomes

Por Zahoránszky-Kőhalmi, Gergely, Bologa, Cristian G., Ursu, Oleg, Oprea, Tudor I.
Publicado no J Cheminform (2016)

BDDCS, the Rule of 5 and Drugability

Por Benet, Leslie Z., Hosey, Chelsea M., Ursu, Oleg, Oprea, Tudor I.
Publicado no Adv Drug Deliv Rev (2016)

The ins and outs of GPR30: a transmembrane estrogen receptor

Por Prossnitz, Eric R., Oprea, Tudor I., Sklar, Larry A., Arterburn, Jeffrey B.
Publicado em 2008

Scaffold Topologies I: Exhaustive Enumeration up to 8 Rings

Por Pollock, Sara N., Coutsias, Evangelos A., Wester, Michael J., Oprea, Tudor I.
Publicado em 2008