Identification of a functional water channel in cytochrome P450 enzymes
Cytochrome P450 enzymes are monooxygenases that contain a functional heme b group linked to a conserved cysteine with a thiolate bond. In the native state, the central iron atom is hexacoordinated with a covalently bound water molecule. The exclusion of solvent molecules from the active site is esse...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20053/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122160/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2133 |
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