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Novel Chemical Space Exploration via Natural Products

Natural products (NPs) are a rich source of novel compound classes and new drugs. In the present study we have used the chemical space navigation tool ChemGPS-NP to evaluate the chemical space occupancy by NPs and bioactive medicinal chemistry compounds from the database WOMBAT. The two sets differ...

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Detalhes bibliográficos
Main Authors: Rosén, Josefin, Gottfries, Johan, Muresan, Sorel, Backlund, Anders, Oprea, Tudor I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696019/
https://ncbi.nlm.nih.gov/pubmed/19265440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801514w
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