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Scaffold Topologies II: Analysis of Chemical Databases

We have systematically enumerated graph representations of scaffold topologies for up to 8-ring molecules and 4-valence atoms, thus providing coverage of the lower portion of the chemical space of small molecules (Pollock et al.(1)). Here, we examine scaffold topology distributions for several datab...

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Autors principals: Wester, Michael J., Pollock, Sara, Coutsias, Evangelos A., Allu, Tharun Kumar, Muresan, Sorel, Oprea, Tudor I.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807378/
https://ncbi.nlm.nih.gov/pubmed/18605681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci700342h
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