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BDDCS, the Rule of 5 and Drugability

The rule of 5 methodology appears to be as useful today in defining drugability as when it was proposed, but recognizing that the database that we used includes only drugs that successfully reached the market. We do not view additional criteria necessary nor did we find significant deficiencies in t...

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Detalhes bibliográficos
Publicado no:Adv Drug Deliv Rev
Main Authors: Benet, Leslie Z., Hosey, Chelsea M., Ursu, Oleg, Oprea, Tudor I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910824/
https://ncbi.nlm.nih.gov/pubmed/27182629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2016.05.007
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