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BDDCS Class Prediction for New Molecular Entities

The Biopharmaceutics Drug Disposition Classification System (BDDCS) was successfully employed for predicting drug-drug interactions (DDIs) with respect to drug metabolizing enzymes (DMEs), drug transporters and their interplay. The major assumption of BDDCS is that the extent of metabolism (EoM) pre...

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Détails bibliographiques
Auteurs principaux: Broccatelli, Fabio, Cruciani, Gabriele, Benet, Leslie Z., Oprea, Tudor I.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295927/
https://ncbi.nlm.nih.gov/pubmed/22224483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp2004302
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